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aptx  (Santa Cruz Biotechnology)


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    Structured Review

    Santa Cruz Biotechnology aptx
    Protein levels of key cGAS-STING effector proteins are affected by <t>APTX</t> KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and <t>for</t> <t>IRF3</t> and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.
    Aptx, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 91/100, based on 3 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/aptx/pmc10754971-265-0-12?v=Santa+Cruz+Biotechnology
    Average 91 stars, based on 3 article reviews
    aptx - by Bioz Stars, 2026-08
    91/100 stars

    Images

    1) Product Images from "The DNA repair enzyme, aprataxin, plays a role in innate immune signaling"

    Article Title: The DNA repair enzyme, aprataxin, plays a role in innate immune signaling

    Journal: Frontiers in Aging Neuroscience

    doi: 10.3389/fnagi.2023.1290681

    Protein levels of key cGAS-STING effector proteins are affected by APTX KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and for IRF3 and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.
    Figure Legend Snippet: Protein levels of key cGAS-STING effector proteins are affected by APTX KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and for IRF3 and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Techniques Used: Transfection, Western Blot, Staining



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    Protein levels of key cGAS-STING effector proteins are affected by <t>APTX</t> KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and <t>for</t> <t>IRF3</t> and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.
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    Image Search Results


    Protein levels of key cGAS-STING effector proteins are affected by APTX KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and for IRF3 and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Journal: Frontiers in Aging Neuroscience

    Article Title: The DNA repair enzyme, aprataxin, plays a role in innate immune signaling

    doi: 10.3389/fnagi.2023.1290681

    Figure Lengend Snippet: Protein levels of key cGAS-STING effector proteins are affected by APTX KO during dsDNA stimulation. Microglia cells were transfected with dsDNA and harvested for western blot analysis. Blots were stained for STING and pSTING (A) and levels quantified in (B,C) , TBK1 and pTBK1 (D) and levels quantified in (E,F) and for IRF3 and pIRF3 (G) quantified in (H,I) . Graphs show mean ± SEM, analyzed by two-way ANOVA, where significance is scored as ns p > 0.05, * p < 0.05, ** p < 0.01, *** p < 0.001.

    Article Snippet: APTX (sc-374108), IRF3 (SL-12, sc-33641) and Rig1 (D12, sc-376845) antibodies were from Santa Cruz and Actin (A5441) was from Merck.

    Techniques: Transfection, Western Blot, Staining